Document Detail

Studies on hypothalamo-pituitary corticoliberin system. II. Corticotropin-releasing factor (CRF) and neurophysin (NP) immunoreactive neurocytes in the hamster.
MedLine Citation:
PMID:  3502464     Owner:  NLM     Status:  MEDLINE    
The aim of the study was to investigate CRF- and neurophysin-immunoreactive neurocytes in hypothalamo-pituitary system of the hamster. CRF-immunoreactive nerve fibers were observed mainly in the outer layer of the median eminence and pituitary stalk and also in the neurohypophysis. On the contrary, neither intermediate lobe nor anterior pituitary contained CRF-immunoassayable substance. The pattern of distribution of neurophysin-immunoreactive fibres was different from CRF-immunoreactive fibres as far as a median eminence, pituitary stalk and neurohypophysis are concerned. Between the tannocytes of the III ventricle and nervous fibres forming the internal layer of the median eminence a CRF- and neurophysin-immunoreactive perikaryons of neurocytes were found. Results of the study suggest regulatory function of CRF-immunoreactive neurons of the hamster hypothalamo-pituitary system in controlling of ACTH secretion. Moreover, the distribution of CRF-immunoreactive substances in hamster hypothalamo-pituitary system shows some peculiarities if compared with other rodents.
B Miśkowiak
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society     Volume:  25     ISSN:  0239-8508     ISO Abbreviation:  Folia Histochem. Cytobiol.     Publication Date:  1987  
Date Detail:
Created Date:  1988-07-12     Completed Date:  1988-07-12     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8502651     Medline TA:  Folia Histochem Cytobiol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  209-14     Citation Subset:  IM    
Department of Histology and Embryology, Academy of Medicine, Poznań, Poland.
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MeSH Terms
Adrenal Cortex / cytology,  physiology
Body Weight
Corticotropin-Releasing Hormone / immunology,  physiology*
Hypothalamo-Hypophyseal System / physiology*
Neurons / cytology*,  immunology
Neurophysins / immunology*,  physiology,  secretion
Pituitary Gland / analysis,  anatomy & histology
Species Specificity
Reg. No./Substance:
0/Neurophysins; 9015-71-8/Corticotropin-Releasing Hormone

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