| Studies on human pure pancreatic juice collected by endoscopic retrograde catheterization of the papilla. | |
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MedLine Citation:
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PMID: 729999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pure pancreatic juice was collected from 8 subjects by endoscopic retrograde cannulation of the papilla. Samples were collected at 1 minute intervals for 20 minutes after rapid intravenous injection of secretin (Eisai, 1u/kg) and for 10 to 15 minutes after rapid intravenous injection of CCK-PZ (1 U/kg). Three hydrolases (amylase, chymotrypsinogen and lipase) showed nonparallel secretory pattern. Lipase was proportionally more stimulated than chymotrypsinogen and chymotrypsinogen was more stimulated than amylase by CCK-PZ stimulation. However, in one subject the secretion of three hydrolases was parallel and in another subject lipase and chymotrypsinogen showed parallelism. Samples collected at "wash out" period showed quite high enzyme and protein concentration with specific activity and enzyme ratio not different from those of samples collected at peak period of CCK-PZ stimulation. Normal ranges were estimated in peak flow rate per minute, peak enzyme concentration, specific activity of enzymes, maximal enzyme output per minute and maximal bicarbonate concentration. |
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Authors:
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H Harada; A Ono; N Yamamoto; I Ikubo; A Negron; T Hayashi; T Sato; K Mishima; I Kimura |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gastroenterologia Japonica Volume: 13 ISSN: 0435-1339 ISO Abbreviation: Gastroenterol. Jpn. Publication Date: 1978 |
Date Detail:
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Created Date: 1979-03-24 Completed Date: 1979-03-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0152744 Medline TA: Gastroenterol Jpn Country: JAPAN |
Other Details:
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Languages: eng Pagination: 383-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amylases
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secretion* Catheterization / methods Cholecystokinin / pharmacology Chymotrypsinogen / secretion* Endoscopy / methods Humans Lipase / secretion* Pancreatic Ducts Pancreatic Juice / enzymology*, secretion Specimen Handling / methods* |
| Chemical | |
Reg. No./Substance:
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9011-97-6/Cholecystokinin; 9035-75-0/Chymotrypsinogen; EC 3.1.1.3/Lipase; EC 3.2.1.-/Amylases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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