Document Detail

Studies on the epidemiology of colitis due to Clostridium difficile in hamsters.
MedLine Citation:
PMID:  7217712     Owner:  NLM     Status:  MEDLINE    
Hamsters treated with vancomycin developed enterocolitis significantly more often in a conventional animal room than in a room designed to prevent cross-infection with Clostridium difficile. In the conventional room C. difficile was isolated from cages, food racks, floors, buckets, the hands of caretakers, and the stools of animals with enterocolitis but not from untreated hamsters, air, or food from freshly opened bags. C. difficile was not isolated from environmental sources in the clean room. It was not possible to determine which of the sources of the organism was most important in its spread. Cross-infection with C. difficile may be important in the pathogenesis of antibiotic-associated enterocolitis in hamster colonies.
R Toshniwal; J Silva; R Fekety; K H Kim
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  143     ISSN:  0022-1899     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  1981 Jan 
Date Detail:
Created Date:  1981-06-23     Completed Date:  1981-06-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  AIM; IM    
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MeSH Terms
Clostridium / isolation & purification*
Clostridium Infections / transmission*
Colitis / etiology*
Cross Infection / prevention & control*
Enterocolitis, Pseudomembranous / etiology
Mesocricetus / microbiology
Vancomycin / adverse effects
Grant Support
Reg. No./Substance:

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