Document Detail

Studies on the distribution of abnormal cells in cytologic preparations. VI. Pressure exerted by the gynecologist during smearing.
MedLine Citation:
PMID:  6683215     Owner:  NLM     Status:  MEDLINE    
A model system consisting of exfoliated abnormal cells and acellular viscous, mucus-like material was used to investigate the effect of the pressure exerted during smearing on the number of abnormal cells present in the preparations. Smears were made with a cotton swab applicator from left to right with parallel strokes, without overlapping smearing and without rotating the instrument of cell collection. Light and heavy pressures done during smearing procedure were recorded by the aid of an automatic scale. By means of the smearing technique, a gradual decrease in the total number of cells was recorded along the pathway of smearing. By using heavy pressure, however, cell accumulation also occurred at the end of the pathway of the last smearing strokes. Smears made with heavy pressure contained 13% more tumor cells than those made with light pressure. It is concluded that the pressure exerted by the operator during smearing may be an important parameter influencing both the number and the distribution of abnormal cells on smear preparations. These considerations may be of significance in screening programs for tumor cell detection.
C A Rubio; N Stormby; Y Kock; P Thomassen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic oncology     Volume:  15     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1983-08-26     Completed Date:  1983-08-26     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  391-5     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Ehrlich Tumor / pathology
Cell Count
Uterine Cervical Neoplasms / pathology
Vaginal Smears / methods*,  standards

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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