Document Detail

Studies on cytotoxicity of nickel ions using C3H10T1/2 fibroblast cells.
MedLine Citation:
PMID:  11251779     Owner:  NLM     Status:  MEDLINE    
Cytotoxicity of Ni ions were examined using C3H mouse derived 10T1/2 fibroblast cells. It became evident that Ni ions had dose-dependent cytotoxicity. The cell number incubated in DME medium containing 0.04 mM/L Ni ion for 6 days was reduced to half that in control DME medium without Ni. The cell totally disappeared in DME medium containing 2 mM/L Ni ion. The dissolution of Ni ions from Ni-containing metallic restorations must be lower than these concentration levels so that oral tissues might not be damaged. No neoplastic transformation was found on all cells examined.
M Taira; M S Toguchi; Y Hamada; M Okazaki; J Takahashi; R Ito; S Toyosawa; N Ijyuin
Related Documents :
9615759 - Combined effects of tnp-470 and taxol in human non-small cell lung cancer cell lines.
20932619 - Antagonism of phenanthrene cytotoxicity for human embryo lung fibroblast cell line hfl-...
19921789 - Alasmontamine a, a first tetrakis monoterpene indole alkaloid from tabernaemontana eleg...
6825119 - Role of glutathione in the hypoxic cell cytotoxicity of misonidazole.
6620399 - Response of isolated hepatocytes to organic and inorganic cytotoxins.
11251779 - Studies on cytotoxicity of nickel ions using c3h10t1/2 fibroblast cells.
159319 - Cell-mediated lympholysis by human maternal and neonatal lymphocytes: mother's reactivi...
22821479 - Journal of cellular physiology: volume 227, number 11, november 2012.
9298849 - Regulation of energy metabolism by neurotransmitters in astrocytes in primary culture a...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of oral rehabilitation     Volume:  27     ISSN:  0305-182X     ISO Abbreviation:  J Oral Rehabil     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-03-19     Completed Date:  2001-04-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0433604     Medline TA:  J Oral Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  1068-72     Citation Subset:  D; IM    
Department of Dental Materials Science and Technology, Osaka University Faculty of Dentistry, Osaka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cell Line
Cell Survival / drug effects
Culture Media
Dose-Response Relationship, Drug
Fibroblasts / drug effects*
Lethal Dose 50
Mice, Inbred C3H
Nickel / toxicity*
Nitric Acid / chemistry
Sodium Bicarbonate / chemistry
Reg. No./Substance:
0/Culture Media; 0/Ions; 144-55-8/Sodium Bicarbonate; 7440-02-0/Nickel; 7697-37-2/Nitric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Physical properties of resinous cements: an in vitro study.
Next Document:  Rehabilitation of biting abilities in patients with different types of dental prostheses.