Document Detail


Studies on the conjugation of leukotriene B4 with proteins for development of a radioimmunoassay for leukotriene B4.
MedLine Citation:
PMID:  6318274     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Leukotriene B4 (LTB4) (I) has been converted to its N-(3-amino-propyl)amide derivative (III) and to its hydrazide derivative (VII) via LTB4 delta-lactone. The amide (III) was coupled with Bovine Serum Albumin using 1,5-difluoro-2,4-dinitrobenzene as coupling agent. The hydrazide (VII), was coupled with Hemocyanin (Keyhole Limpet) (KLH) using 6-N-maleimidohexanoic acid chloride as coupling agent.
Authors:
R N Young; R Zamboni; J Rokach
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prostaglandins     Volume:  26     ISSN:  0090-6980     ISO Abbreviation:  Prostaglandins     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0320271     Medline TA:  Prostaglandins     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  605-13     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chemical Phenomena
Chemistry
Leukotriene B4 / analysis*
Radioimmunoassay / methods
Serum Albumin, Bovine*
Chemical
Reg. No./Substance:
0/Serum Albumin, Bovine; 71160-24-2/Leukotriene B4

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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