Document Detail


Studies on chiasma frequency and distribution in two fertile men carrying reciprocal translocations; one with a t(9;10) karyotype and one with a t(Y;10) karyotype.
MedLine Citation:
PMID:  6500577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The frequency and distribution of chiasmata was investigated in two fertile carriers of reciprocal translocations, one with a 46,XY,t(9;10)(p22;q24) karyotype and one with a 46,X,-Y,+der(Y),t(Y;10)(q12;q24) karyotype. In both cases the chromosomes involved in the translocation showed an increase in chiasma frequency in comparison to karyotypically normal controls and in both cases this increase was localised, affecting only one interstitial segment of each translocation quadrivalent. In the t(9;10) case chiasmata appeared in substantial numbers in a novel location, the proximal two thirds of 9p, while in the t(Y;10) case chiasmata appeared in a conventional location, the medial region of 10q, but at an increased frequency. Furthermore there was evidence for inter-chromosomal effects in the t(9;10) case.
Authors:
D A Laurie; R W Palmer; M A Hultén
Related Documents :
18182347 - Evaluation of the results of cordocentesis.
15633177 - Mosaic trisomy 4: long-term outcome on the first reported liveborn.
8025097 - Antenatal diagnosis of sacrococcygeal teratoma with hydrops fetalis; a case report.
9234017 - An outbreak of abortion in mares associated with salmonella abortusequi infection.
23821247 - A case of intrauterine diagnosed posterior fossa dermoid presenting in childhood.
899787 - Primary cerebral melanomas. report of six cases and a review of the literature.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Human genetics     Volume:  68     ISSN:  0340-6717     ISO Abbreviation:  Hum. Genet.     Publication Date:  1984  
Date Detail:
Created Date:  1985-01-22     Completed Date:  1985-01-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7613873     Medline TA:  Hum Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  235-47     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Chromosomes, Human, 6-12 and X*
Crossing Over, Genetic*
Fertility
Humans
Male
Meiosis
Sex Chromosome Aberrations / genetics*
Spermatogenesis
Translocation, Genetic*
Y Chromosome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Human genes for glutathione S-transferases.
Next Document:  A new alpha 2HS-glycoprotein allele (AHS*5) in two Japanese families.