Document Detail

Studies of basal and peak acid output with an augmented histamine test.
MedLine Citation:
PMID:  13969448     Owner:  NLM     Status:  MEDLINE    
On the basis that the most repeatable measurement of acid output of the stomach is the peak half hour after an augmented dose of histamine, the author suggests a modification of the Kay test, including titration of the gastric juice to neutrality and measurement of the chloride concentration. The aspiration tube was sited fluoroscopically. It is suggested that the ;peak half hour' should be substituted for the period 15-45 minutes after administration of histamine. This modification is supported by the presented data. It should be noted, however, that the titration technique has also been modified. The ranges of basal and maximum gastric secretion (volume, acidity, acid output, parietal and non-parietal components) in 20 normal males and 20 normal females are presented and analysed for differences of age and sex. Both basal and maximum (histamine stimulated) gastric secretion declined with age, more so in women than in men. ;Maximum' gastric secretion was greater in men than in women, especially in older subjects.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gut     Volume:  4     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1963 Jun 
Date Detail:
Created Date:  1963-12-01     Completed Date:  1998-11-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  136-44     Citation Subset:  OM    
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MeSH Terms
Gastric Acidity Determination*
Reg. No./Substance:

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