| Structured exercise does not stabilize cognitive function in individuals with mild cognitive impairment residing in a structured living facility. | |
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MedLine Citation:
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PMID: 21244306 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Exercise has been shown to have positive effects on the brain and cognition in healthy older adults, though no study has directly examined possible cognitive benefits of formal exercise programs in persons with mild cognitive impairment (MCI) living in structured facilities. Thirty-one participants completed neuropsychological testing and measures of cardiovascular fitness at baseline and after 6 months of a structured exercise program that included aerobic and resistance training. While exercise improved cardiovascular fitness in persons with MCI, there was no improvement in cognitive function. Rather, MCI patients in this sample declined in performance on several tests sensitive to Alzheimer's disease. Examined in the context of past work, it appears exercise may be beneficial prior to the onset of MCI, though less helpful after its onset. |
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Authors:
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Lindsay A Miller; Mary Beth Spitznagel; Susan Busko; Vanessa Potter; Judi Juvancic-Heltzel; Nancy Istenes; Ellen Glickman; John Gunstad |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2011-01-19 |
Journal Detail:
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Title: The International journal of neuroscience Volume: 121 ISSN: 1563-5279 ISO Abbreviation: Int. J. Neurosci. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-02-18 Completed Date: 2012-01-05 Revised Date: 2012-04-04 |
Medline Journal Info:
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Nlm Unique ID: 0270707 Medline TA: Int J Neurosci Country: England |
Other Details:
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Languages: eng Pagination: 218-23 Citation Subset: IM |
Affiliation:
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Department of Psychology, Kent State University, Kent Hall, Kent, Ohio 44242, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Assisted Living Facilities* Cognition Disorders / diagnosis*, physiopathology, therapy* Exercise / physiology, psychology Exercise Therapy / methods*, psychology Female Humans Male Physical Fitness / physiology, psychology Resistance Training / methods Treatment Failure |
| Grant Support | |
ID/Acronym/Agency:
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DK075119/DK/NIDDK NIH HHS; HL089311/HL/NHLBI NIH HHS; R01 DK075119-04/DK/NIDDK NIH HHS; R01 HL089311-04/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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