| Structure versus processing deficits in Alzheimer's disease, a matter of degree: a comment on Storms et al. (2003). | |
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MedLine Citation:
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PMID: 12803437 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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G. Storms, T. Dirikx, J. Saerens, S. Verstraeten, and P. P. De Deyn (2003) argued that multidimensional scaling studies are ill-suited for investigating semantic deficits in individuals diagnosed with dementia of the Alzheimer type (DAT) because such individuals show great inter- and intraindividual variability in their proximity judgments. Discussed in this commentary are (a) the possible role of attentional set in producing inconsistent performance across trials, (b) the implications of attentional factors on the structure versus process debate, and (c) the inevitable semantic degradation following severe progression of the disease. A framework is presented for considering nonlinear performance differences as a function of attentional demands of the task, vulnerability of the semantic representation, and progression of the disease. |
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Authors:
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Keith A Hutchison; David A Balota |
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Publication Detail:
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Type: Comment; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Neuropsychology Volume: 17 ISSN: 0894-4105 ISO Abbreviation: Neuropsychology Publication Date: 2003 Apr |
Date Detail:
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Created Date: 2003-06-13 Completed Date: 2003-07-14 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8904467 Medline TA: Neuropsychology Country: United States |
Other Details:
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Languages: eng Pagination: 306-9; discussion 323-9 Citation Subset: IM |
Affiliation:
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Department of Psychology, Washington University, St Louis, Missouri 63130, USA. khutch@artsci.wustl.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alzheimer Disease
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psychology Cluster Analysis* Data Interpretation, Statistical* Disease Progression Humans Individuality Memory Disorders / psychology Memory, Short-Term / physiology Neuropsychological Tests / statistics & numerical data* Semantics* |
| Grant Support | |
ID/Acronym/Agency:
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P01 AG101993/AG/NIA NIH HHS |
| Comments/Corrections | |
Comment On:
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Neuropsychology. 2003 Apr;17(2):289-301
[PMID:
12803435
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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