Document Detail


Structure versus processing deficits in Alzheimer's disease, a matter of degree: a comment on Storms et al. (2003).
MedLine Citation:
PMID:  12803437     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
G. Storms, T. Dirikx, J. Saerens, S. Verstraeten, and P. P. De Deyn (2003) argued that multidimensional scaling studies are ill-suited for investigating semantic deficits in individuals diagnosed with dementia of the Alzheimer type (DAT) because such individuals show great inter- and intraindividual variability in their proximity judgments. Discussed in this commentary are (a) the possible role of attentional set in producing inconsistent performance across trials, (b) the implications of attentional factors on the structure versus process debate, and (c) the inevitable semantic degradation following severe progression of the disease. A framework is presented for considering nonlinear performance differences as a function of attentional demands of the task, vulnerability of the semantic representation, and progression of the disease.
Authors:
Keith A Hutchison; David A Balota
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Publication Detail:
Type:  Comment; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neuropsychology     Volume:  17     ISSN:  0894-4105     ISO Abbreviation:  Neuropsychology     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-06-13     Completed Date:  2003-07-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8904467     Medline TA:  Neuropsychology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  306-9; discussion 323-9     Citation Subset:  IM    
Affiliation:
Department of Psychology, Washington University, St Louis, Missouri 63130, USA. khutch@artsci.wustl.edu
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MeSH Terms
Descriptor/Qualifier:
Alzheimer Disease / psychology
Cluster Analysis*
Data Interpretation, Statistical*
Disease Progression
Humans
Individuality
Memory Disorders / psychology
Memory, Short-Term / physiology
Neuropsychological Tests / statistics & numerical data*
Semantics*
Grant Support
ID/Acronym/Agency:
P01 AG101993/AG/NIA NIH HHS
Comments/Corrections
Comment On:
Neuropsychology. 2003 Apr;17(2):289-301   [PMID:  12803435 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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