Document Detail


Structure of the thioredoxin-fold domain of human phosducin-like protein 2.
MedLine Citation:
PMID:  19193988     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Human phosducin-like protein 2 (hPDCL2) has been identified as belonging to subgroup II of the phosducin (Pdc) family. The members of this family share an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. The X-ray crystal structure of the Trx-fold domain of hPDCL2 was solved at 2.70 A resolution and resembled the Trx-fold domain of rat phosducin. Comparative structural analysis revealed the structural basis of their putative functional divergence.
Authors:
Xiaochu Lou; Rui Bao; Cong Zhao Zhou; Yuxing Chen
Related Documents :
16018968 - Structural characterization of the mit domain from human vps4b.
18763088 - Mutational analysis of the structure basis for the multimerization function of nifa cen...
18264588 - C-terminal region of the active domain enhances enzymatic activity in dinoflagellate lu...
8380468 - Mapping of a major surface-exposed site in herpes simplex virus protein vmw65 to a regi...
21056978 - A two-step mechanism for the folding of actin by the yeast cytosolic chaperonin.
1527068 - Characterization of a cholecystokinin 8-generating endoprotease purified from rat brain...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-31
Journal Detail:
Title:  Acta crystallographica. Section F, Structural biology and crystallization communications     Volume:  65     ISSN:  1744-3091     ISO Abbreviation:  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-05     Completed Date:  2009-09-30     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  101226117     Medline TA:  Acta Crystallogr Sect F Struct Biol Cryst Commun     Country:  England    
Other Details:
Languages:  eng     Pagination:  67-70     Citation Subset:  IM    
Affiliation:
Institute of Protein Research, Tongji University, Shanghai 200092, People's Republic of China.
Data Bank Information
Bank Name/Acc. No.:
PDB/3EVIA;  3EVIB
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Carrier Proteins / chemistry*
Crystallography, X-Ray
Humans
Nerve Tissue Proteins / chemistry*
Protein Folding*
Protein Structure, Tertiary
Rats
Thioredoxins / chemistry*
Chemical
Reg. No./Substance:
0/Carrier Proteins; 0/Nerve Tissue Proteins; 0/PDCL2 protein, human; 52500-60-4/Thioredoxins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Acquired pericentric inversion of chromosome 9 in acute myeloid leukemia.
Next Document:  Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.