Document Detail

Structure of the thioredoxin-fold domain of human phosducin-like protein 2.
MedLine Citation:
PMID:  19193988     Owner:  NLM     Status:  MEDLINE    
Human phosducin-like protein 2 (hPDCL2) has been identified as belonging to subgroup II of the phosducin (Pdc) family. The members of this family share an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. The X-ray crystal structure of the Trx-fold domain of hPDCL2 was solved at 2.70 A resolution and resembled the Trx-fold domain of rat phosducin. Comparative structural analysis revealed the structural basis of their putative functional divergence.
Xiaochu Lou; Rui Bao; Cong Zhao Zhou; Yuxing Chen
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-31
Journal Detail:
Title:  Acta crystallographica. Section F, Structural biology and crystallization communications     Volume:  65     ISSN:  1744-3091     ISO Abbreviation:  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-05     Completed Date:  2009-09-30     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  101226117     Medline TA:  Acta Crystallogr Sect F Struct Biol Cryst Commun     Country:  England    
Other Details:
Languages:  eng     Pagination:  67-70     Citation Subset:  IM    
Institute of Protein Research, Tongji University, Shanghai 200092, People's Republic of China.
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MeSH Terms
Carrier Proteins / chemistry*
Crystallography, X-Ray
Nerve Tissue Proteins / chemistry*
Protein Folding*
Protein Structure, Tertiary
Thioredoxins / chemistry*
Reg. No./Substance:
0/Carrier Proteins; 0/Nerve Tissue Proteins; 0/PDCL2 protein, human; 52500-60-4/Thioredoxins

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