Document Detail

Structure of motivation using food demand in mice.
MedLine Citation:
PMID:  21549728     Owner:  NLM     Status:  MEDLINE    
Most animals have evolved to be foragers for food. We discriminate two types of foraging, the cost to locate or obtain access to the food, and the unit cost to consume the food once it is nearby. Using closed economy studies in normal weight and genetically obese mice, we have examined the effect of either access and/or unit cost on food demand and meal patterns. We also have included wheel running either as a voluntary activity or as an access cost. Our results showed that the demand functions differ between normal, exercising, and genetically obese mice, and that changes in intake normally occur via changes in the size of individual feeding bouts or meals. In contrast, changes in access cost have only a small effect on food demand but have large effects on the pattern of intake--on meal size and the number of meals taken. Thus, although food intake is sensitive to effort, the type of effort and the mode in which it is applied is critically important. These data are discussed in terms of potential economic strategies that could address the human obesity epidemic, for example by maximally targeting meal size and/or snacking behavior.
Deniz Atalayer; Neil E Rowland
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Publication Detail:
Type:  Journal Article     Date:  2011-05-01
Journal Detail:
Title:  Physiology & behavior     Volume:  104     ISSN:  1873-507X     ISO Abbreviation:  Physiol. Behav.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-06-03     Completed Date:  2011-10-14     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  15-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
University of Florida, Gainesville, United States.
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MeSH Terms
Body Weight
Eating / psychology*
Feeding Behavior / psychology*
Motivation / physiology*
Reinforcement Schedule
Grant Support
R01 DK064712-03/DK/NIDDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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