| Structure, function and biosynthesis of O(2)-tolerant hydrogenases. | |
| | |
MedLine Citation:
|
PMID: 23321533 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Molecular hydrogen (H(2)) is used as an energy source or a way to deposit excess reducing power by a wide range of microorganisms. Both H(2) oxidation and production are catalysed by hydrogenases. As these metalloenzymes are usually exquisitely O(2) sensitive, H(2) metabolism under aerobic conditions, which is known as O(2)-tolerant H(2) cycling, involves hydrogenases that have undergone structural and catalytic adaptations and requires a dedicated biosynthetic machinery. Here, we discuss recent high-resolution crystal structure analyses of a particular subtype of [NiFe]-hydrogenase that is predominantly found in aerobic or facultative aerobic H(2)-oxidizing bacteria. These data have provided insights into the underlying molecular strategies that allow sustained biological conversion of H(2) in the presence of O(2). |
| | |
Authors:
|
Johannes Fritsch; Oliver Lenz; Bärbel Friedrich |
Related Documents
:
|
23521283 - Competition between the pseudogap and superconducting states of bi_{2}sr_{2}ca_{0.92}y_... 20353243 - Structural characterization and biological fluid interaction of sol-gel-derived mg-subs... 21587433 - Triimidazolium tris-(pyridine-2,6-di-carboxyl-ato)dysprosate(iii) trihydrate. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Nature reviews. Microbiology Volume: 11 ISSN: 1740-1534 ISO Abbreviation: Nat. Rev. Microbiol. Publication Date: 2013 Feb |
Date Detail:
|
Created Date: 2013-01-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101190261 Medline TA: Nat Rev Microbiol Country: England |
Other Details:
|
Languages: eng Pagination: 106-14 Citation Subset: IM |
Affiliation:
|
Mikrobiologie, Institut für Biologie, Humboldt-Universität zu Berlin, Chausseestraße 117, 10115 Berlin, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Microbial life under extreme energy limitation.
Next Document: West Nile virus infection and immunity.