Document Detail


Structure elucidation of auxofuran, a metabolite involved in stimulating growth of fly agaric, produced by the mycorrhiza helper bacterium Streptomyces AcH 505.
MedLine Citation:
PMID:  17323648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mycorrhiza helper bacterium Streptomyces strain AcH 505 stimulates ectomycorrhiza formation between spruce and fly agaric by supporting fungal growth whereas growth of pathogenic fungi is suppressed. A fungal growth promoting substance was isolated and the chemical structure elucidated by mass spectrometry and NMR spectroscopy. The absolute configuration of the novel fungal growth promoting compound auxofuran (1) was deduced from NMR data with the help of Mosher esters.
Authors:
Simone Keller; Kathrin Schneider; Roderich D Süssmuth
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of antibiotics     Volume:  59     ISSN:  0021-8820     ISO Abbreviation:  J. Antibiot.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-02-27     Completed Date:  2007-03-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151115     Medline TA:  J Antibiot (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  801-3     Citation Subset:  IM    
Affiliation:
Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 124, D-10623 Berlin, Germany.
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MeSH Terms
Descriptor/Qualifier:
Amanita / drug effects*,  growth & development
Benzofurans / chemistry*
Furans / chemistry*
Magnetic Resonance Spectroscopy
Mycorrhizae / growth & development*
Streptomyces / classification,  metabolism*
Chemical
Reg. No./Substance:
0/Benzofurans; 0/Furans; 0/auxofuran

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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