Document Detail


Structure of benzyloxycarbonyl-L-isoleucyl-L-alanyl-alpha- aminoisobutyryl-alpha-aminoisobutyrate methyl ester, Z-L-Ile-L-Ala-Aib-Aib-OMe.
MedLine Citation:
PMID:  1930825     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
C26H40N4O7, Mr = 520.6, tetragonal, P4(3)2(1)2, a = 10.433 (1), c = 54.476 (7) A, V = 5930 (1) A3, Z = 8, Dm = 1.155 (3), Dx = 1.166 Mg m-3, lambda (Cu K alpha) = 1.54178 A, mu = 0.665 mm-1, F(000) = 2240, T = 295 K, R = 0.057 for 2037 observed reflections. The tetrapeptide adopts a type II beta-turn conformation with an extremely weak 4----1 intramolecular hydrogen bond [3.479 (7) A]. The molecules are held together in the crystal by three kinds of N-H---O intermolecular hydrogen bonds.
Authors:
T Taga; S Hourai; K Machida; T Fujita; T Ichihara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta crystallographica. Section C, Crystal structure communications     Volume:  47 ( Pt 7)     ISSN:  0108-2701     ISO Abbreviation:  Acta Crystallogr C     Publication Date:  1991 Jul 
Date Detail:
Created Date:  1991-12-23     Completed Date:  1991-12-23     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8305826     Medline TA:  Acta Crystallogr C     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  1494-6     Citation Subset:  IM    
Affiliation:
Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Anti-Bacterial Agents* / chemistry
Hydrogen-Ion Concentration
Models, Molecular
Molecular Sequence Data
Molecular Structure
Oligopeptides / chemistry*
Peptide Fragments / chemistry
Peptides / chemistry
Protein Conformation
X-Ray Diffraction
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Oligopeptides; 0/Peptide Fragments; 0/Peptides; 135788-75-9/benzyloxycarbonyl-isoleucyl-alanyl-alpha-aminoisobutyryl-alpha-aminoisobutyrate methyl ester; 66554-87-8/trichopolyn

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