Document Detail

Structure activity relationships of stendomycin, a lipopeptide antibiotic from Streptomyces.
MedLine Citation:
PMID:  1406345     Owner:  NLM     Status:  MEDLINE    
A strain of Streptomyces which produced stendomycin, a lipopeptide antibiotic, was grown in culture media containing various amino acids as nitrogen substrates. The nature of the fatty acid component of stendomycin was dependent on the nature of the amino acid present in the medium, but this did not affect antibiotic activity. Modifications in the peptide moiety resulted in a loss of antifungal activity.
B Losilla; M T Pommier; N Bonnaveiro; A Cremieux; G Michel
Related Documents :
468725 - Congeners of etamycin produced by streptomyces griseoviridus.
10030025 - Effect of permeabilizers on antibiotic sensitivity of pseudomonas aeruginosa.
23487785 - Omega-3 fatty acids lower blood pressure by directly activating large-conductance ca²...
23448265 - Indole-3-acetic acid biosynthetic pathway and aromatic amino acid aminotransferase acti...
7378435 - Changes in mitochondrial lipids of rat kidney during ischemia.
9433765 - Resin glycosides. xxv. multifidins i and ii, new jalapins, from the seed of quamoclit x...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Microbios     Volume:  71     ISSN:  0026-2633     ISO Abbreviation:  Microbios     Publication Date:  1992  
Date Detail:
Created Date:  1992-11-23     Completed Date:  1992-11-23     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0207257     Medline TA:  Microbios     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  75-80     Citation Subset:  IM    
Laboratoire de Biochimie Microbienne, Université Claude Bernard, Lyon I, Villeurbanne, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acids
Anti-Bacterial Agents*
Antifungal Agents / biosynthesis,  chemistry,  pharmacology*
Fatty Acids / analysis
Nitrogen / metabolism
Peptide Biosynthesis
Peptides / chemistry,  pharmacology*
Streptomyces / metabolism*
Structure-Activity Relationship
Reg. No./Substance:
0/Amino Acids; 0/Anti-Bacterial Agents; 0/Antifungal Agents; 0/Fatty Acids; 0/Lipids; 0/Peptides; 11006-78-3/stendomycin; 7727-37-9/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cell surface saccharide differences in drug-susceptible and drug-resistant strains of Trichomonas va...
Next Document:  Molecular cloning and nucleotide sequencing of a novel aminoglycoside 6'-N-acetyltransferase gene fr...