Document Detail


Structure and activity of JAC1 J-domain implicate the involvement of the cochaperone activity with HSC70 in chloroplast photorelocation movement.
MedLine Citation:
PMID:  21139434     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Chloroplast photorelocation movement towards weak light and away from strong light is essential for plants to adapt to the fluctuation of ambient light conditions. In the previous study, we showed that blue light receptor phototropins mediated blue light-induced chloroplast movement in Arabidopsis by regulating short actin filaments localized at the chloroplast periphery (cp-actin filaments) rather than actin cables in the cytoplasm. However, the signaling pathway for the chloroplast photorelocation movement is still unclear. We also identified JAC1 (J-domain protein required for chloroplast accumulation response 1) as an essential component for the accumulation response and dark positioning in Arabidopsis. We recently determined the crystal structure of the J-domain of JAC1. The JAC1 J-domain has a positively charged surface, which forms a putative interface with the Hsc70 chaperone by analogy to that of bovine auxilin. Furthermore, the mutation of the highly conserved HPD motif in the JAC1 J-domain impaired the in vivo activity of JAC1. These data suggest that JAC1 cochaperone activity with HSC70 is essential for chloroplast photorelocation movement.
Authors:
Noriyuki Suetsugu; Akira Takano; Daisuke Kohda; Masamitsu Wada
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Publication Detail:
Type:  Journal Article     Date:  2010-12-01
Journal Detail:
Title:  Plant signaling & behavior     Volume:  5     ISSN:  1559-2324     ISO Abbreviation:  Plant Signal Behav     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-04-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101291431     Medline TA:  Plant Signal Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1602-6     Citation Subset:  IM    
Affiliation:
Department of Biology, Faculty of Sciences; Kyushu University; Fukuoka, Japan.
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