Document Detail


Structure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pylori.
MedLine Citation:
PMID:  23039228     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
DATABASE: Structural data have been deposited in the Protein Data Bank under accession number 3QDL.
Authors:
Marta Martínez-Júlvez; Adriana L Rojas; Igor Olekhnovich; Vladimir Espinosa Angarica; Paul S Hoffman; Javier Sancho
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-11-07
Journal Detail:
Title:  The FEBS journal     Volume:  279     ISSN:  1742-4658     ISO Abbreviation:  FEBS J.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-22     Completed Date:  2013-01-25     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  101229646     Medline TA:  FEBS J     Country:  England    
Other Details:
Languages:  eng     Pagination:  4306-17     Citation Subset:  IM    
Copyright Information:
© 2012 The Authors Journal compilation © 2012 FEBS.
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Anti-Infective Agents / pharmacology
Binding Sites
Flavoproteins / chemistry,  genetics,  metabolism*
Helicobacter pylori / drug effects,  enzymology*
Metronidazole / pharmacology*
Molecular Sequence Data
Nitroreductases / chemistry*,  genetics,  metabolism*
Protein Structure, Secondary
Sequence Homology, Amino Acid
Grant Support
ID/Acronym/Agency:
R01 DK073823/DK/NIDDK NIH HHS; R01DK073823/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Flavoproteins; 140QMO216E/Metronidazole; EC 1.7.-/Nitroreductases
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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