Document Detail


Structural studies of the putative O-specific polysaccharide of Acinetobacter baumannii O24 containing 5,7-diamino-3,5,7,9-tetradeoxy-L-glycero-D-galacto-nonulosonic acid.
MedLine Citation:
PMID:  9428717     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A polysaccharide containing D-GlcN, 2-amino-2,6-dideoxy-L-galactose (L-FucN), and 7-acetamido-5-acylamino-3,5,7,9-tetradeoxy-L-glycero-D-galacto-nonulo sonic acid (LegAX), in which the acyl group (X) is either S-3-hydroxybutyryl (50%) or acetyl (50%), was isolated by mild acid hydrolysis treatment, followed by gel-permeation chromatography, of the water-soluble lipopolysaccharide from Acinetobacter baumannii serogroup O24. The polysaccharide, characterised by means of monosaccharide analyses, partial acid hydrolysis, methylation analysis and NMR studies, was shown to have a linear tetrasaccharide repeating unit, as depicted below. Serological tests indicated that the polymer corresponded to the O24 antigen. -->6)-alpha-D-GlcpNAc-(1-->3)-alpha-L-FucpNAc-(1-->3)-alpha-D-Glcp NAc-(1-->4)-beta-LegpAX-(1-->.
Authors:
S R Haseley; S G Wilkinson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of biochemistry / FEBS     Volume:  250     ISSN:  0014-2956     ISO Abbreviation:  Eur. J. Biochem.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-01-22     Completed Date:  1998-01-22     Revised Date:  2007-07-23    
Medline Journal Info:
Nlm Unique ID:  0107600     Medline TA:  Eur J Biochem     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  617-23     Citation Subset:  IM    
Affiliation:
School of Chemistry, University of Hull, England.
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MeSH Terms
Descriptor/Qualifier:
Acinetobacter / chemistry*
Magnetic Resonance Spectroscopy
O Antigens / chemistry*
Chemical
Reg. No./Substance:
0/O Antigens

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