Document Detail

Structural neuroimaging of geriatric depression.
MedLine Citation:
PMID:  21536166     Owner:  NLM     Status:  MEDLINE    
There is a large literature on the neuroanatomy of late-life depression that continues to grow with the discovery of novel structural imaging techniques along with innovative methods to analyze the images. Such advances have helped identify specific areas, characteristic lesions, and changes in the chemical composition in these regions that might be important in the pathophysiology of this complex disease. This article reviews relevant findings by each structural neuroimaging technique. When validated across many studies, such findings can serve as neuroanatomic markers that can help generate rational hypotheses for future studies to further understanding of geriatric depression.
Sophiya Benjamin; David C Steffens
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Psychiatric clinics of North America     Volume:  34     ISSN:  1558-3147     ISO Abbreviation:  Psychiatr. Clin. North Am.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-03     Completed Date:  2011-10-14     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  7708110     Medline TA:  Psychiatr Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  423-35, ix     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
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MeSH Terms
Aging / pathology*,  psychology*
Brain / pathology*
Depressive Disorder / pathology*,  psychology*
Diffusion Tensor Imaging
Magnetic Resonance Spectroscopy
Organ Size
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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