Document Detail

Structural and histochemical aspects of the pericellular environment in cartilage.
MedLine Citation:
PMID:  239418     Owner:  NLM     Status:  MEDLINE    
Mature cartilage contains pericellular regions of matrix of fine texture, consisting of filamentous material and granules containing proteoglycan. Intercellular matrix contains collagen fibres with structural elements resembling those of the pericellular regions in the spaces between the fibres. Membrane bound bodies may be present at the margin of the pericellular region. Histochemically, chondroitin sulphate is found in the pericellular region in all zones but keratan sulphate is similarly stainable only in the deep zones of ageing cartilage.
R A Stockwell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Philosophical transactions of the Royal Society of London. Series B, Biological sciences     Volume:  271     ISSN:  0962-8436     ISO Abbreviation:  Philos. Trans. R. Soc. Lond., B, Biol. Sci.     Publication Date:  1975 Jul 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503623     Medline TA:  Philos Trans R Soc Lond B Biol Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  243-5     Citation Subset:  IM    
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MeSH Terms
Age Factors
Cartilage, Articular / metabolism,  ultrastructure*
Chondroitin / metabolism
Collagen / analysis
Extracellular Space / analysis*
Keratan Sulfate / metabolism
Microscopy, Electron
Middle Aged
Proteoglycans / analysis
Reg. No./Substance:
0/Proteoglycans; 9007-27-6/Chondroitin; 9007-34-5/Collagen; 9056-36-4/Keratan Sulfate

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