| Structural effects of an innovative surgical technique to repair heart valve defects. | |
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MedLine Citation:
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PMID: 16214494 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The structural and functional effects of the "edge-to-edge" technique on the human mitral valve have been investigated, paying particular attention to the diastolic phase. An advanced finite element model of the valve has been developed, using a hyperelastic material schematization, suitable geometry and constraint conditions, and an effective fluidodynamic analysis. The edge-to-edge suture has been applied on this model and the diastolic phase has been simulated. The results of this calculation show that the operation increases the transvalvular pressure and the maximum stress in the leaflets, which reaches a level similar to that of the systolic phase. The influence of suture position and extension, and the mitral annulus dimension has also been investigated. The results indicate that a lateral location of the stitch is better than a central one, both regarding valve functionality (pressure level and mobility) and internal stresses level, that a longer suture worsens the valve functionality but reduces the stresses level, finally, that the dilatation of the mitral annulus does not affect the valve functionality but increases the stresses level. |
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Authors:
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F Dal Pan; G Donzella; C Fucci; M Schreiber |
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Publication Detail:
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Type: Journal Article Date: 2004-12-08 |
Journal Detail:
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Title: Journal of biomechanics Volume: 38 ISSN: 0021-9290 ISO Abbreviation: J Biomech Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2005-10-10 Completed Date: 2006-01-20 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0157375 Medline TA: J Biomech Country: United States |
Other Details:
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Languages: eng Pagination: 2460-71 Citation Subset: IM |
Affiliation:
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Dipartimento di Ingegneria Meccanica-Università di Brescia,Via Branze 38, 25123, Brescia, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Surgical Procedures
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methods Computer Simulation Elasticity Finite Element Analysis Humans Mitral Valve / physiopathology*, surgery* Mitral Valve Prolapse / diagnosis, physiopathology*, surgery* Models, Cardiovascular* Prognosis Shear Strength Stress, Mechanical Surgery, Computer-Assisted / methods* Suture Techniques Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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