| Structural characterization of teichoic acids from Lactobacillus brevis. | |
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MedLine Citation:
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PMID: 20034620 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Teichoic acids are a major constituent of the cell wall of Gram-positive bacteria. Structural characterization of lipoteichoic and teichoic acids isolated from Lactobacillus brevis was undertaken using 1D and 2D NMR experiments as well as chemical methodology. Compositional analysis indicated the presence of high amounts of glycerol, glucose, and alanine. In the case of LTA octadecenoic acid was also detected. The basic LTA/WTA structure was identified as 1,3-poly(glycerol phosphate) nonstoichiometrically substituted at C-2 of the glycerol residues with D-Ala or alpha-D-Glc. In the case of LTA a higher amount of Ala could be detected and partial alanylation at position C-6 of the Glc could also be observed. |
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Authors:
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Patricia M S?nchez Carballo; Heikki Vilen; Airi Palva; Otto Holst |
Publication Detail:
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Type: Journal Article Date: 2009-12-23 |
Journal Detail:
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Title: Carbohydrate research Volume: 345 ISSN: 1873-426X ISO Abbreviation: Carbohydr. Res. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-09 Completed Date: 2010-06-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0043535 Medline TA: Carbohydr Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 538-42 Citation Subset: IM |
Affiliation:
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Division of Structural Biochemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Germany. psanchez@fz-borstel.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alanine
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chemistry Carbohydrate Sequence Cell Wall / chemistry Glucose / chemistry Glycerol / chemistry Glycerophosphates / chemistry Lactobacillus brevis / chemistry*, cytology Lipopolysaccharides / chemistry Magnetic Resonance Spectroscopy Molecular Structure Stearic Acids / chemistry Teichoic Acids / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/5-octadecenoic acid; 0/Glycerophosphates; 0/Lipopolysaccharides; 0/Stearic Acids; 0/Teichoic Acids; 50-99-7/Glucose; 52007-79-1/polyglycerolphosphate; 56-41-7/Alanine; 56-81-5/Glycerol; 56411-57-5/lipoteichoic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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