Document Detail

Structural basis for mitral valve dysfunction associated with ostium secundum atrial septal defects.
MedLine Citation:
PMID:  8402764     Owner:  NLM     Status:  MEDLINE    
Mitral valve (MV) specimens obtained at operation from 50 patients with ostium secundum atrial septal defect and associated MV dysfunction were studied macro- and microscopically to evaluate the structural lesions. The functional abnormalities in these patients were isolated mitral stenosis, isolated mitral regurgitation, mitral valve prolapse or mitral stenosis with regurgitation. Post-inflammatory lesions were commonly found in those with mitral stenosis who had a past history of rheumatic fever. Patients with mitral valve prolapse had either post-inflammatory lesions or lesions attributable to haemodynamic stress but different from the extensive lesions seen in floppy MV syndrome.
J Joy; C C Kartha; K G Balakrishnan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  82     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1993  
Date Detail:
Created Date:  1993-11-23     Completed Date:  1993-11-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  409-14     Citation Subset:  IM    
Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
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MeSH Terms
Echocardiography, Doppler
Heart Septal Defects, Atrial / pathology*,  physiopathology,  surgery
Heart Valve Prosthesis
Hemodynamics / physiology
Mitral Valve / pathology*,  physiopathology,  surgery
Mitral Valve Insufficiency / pathology*,  physiopathology,  surgery
Mitral Valve Stenosis / pathology*,  physiopathology,  surgery

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