| Strongyloides hyperinfection and hypogammaglobulinemia. | |
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MedLine Citation:
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PMID: 15879034 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report strongyloides hyperinfection in two patients with generalized hypogammaglobulinemia from multiple myeloma and nephrotic syndrome, despite a significant strongyloides-specific immunoglobulin G (IgG) response. In contrast to reports on animals, where human IgG was shown to be a protective antibody, our observation suggests that in humans, immunity to the infective-stage larvae is not protective against the autoinfective larvae, which are the causative agents of strongyloides hyperinfection. |
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Authors:
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Raymond C S Seet; Lee Gong Lau; Paul Ananth Tambyah |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical and diagnostic laboratory immunology Volume: 12 ISSN: 1071-412X ISO Abbreviation: Clin. Diagn. Lab. Immunol. Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-05-09 Completed Date: 2005-10-18 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 9421292 Medline TA: Clin Diagn Lab Immunol Country: United States |
Other Details:
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Languages: eng Pagination: 680-2 Citation Subset: IM |
Affiliation:
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Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074. raymond_seet@nus.edu.sg |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Agammaglobulinemia
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etiology Animals Antibodies, Helminth / blood Antibody Formation / immunology Humans Immunoglobulin G / blood Larva / immunology Male Middle Aged Multiple Myeloma / complications Nephrotic Syndrome / complications Strongyloides / immunology Strongyloidiasis / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Helminth; 0/Immunoglobulin G |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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