| Strong correlation between diet and development of colorectal cancer. | |
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MedLine Citation:
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PMID: 23276917 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Multiple factors have been described among the causes of non-hereditary colorectal cancer. In Western countries, the most common risk factors include upper-middle socioeconomic status and dietary regimens rich in proteins and animal fats. High consumption of red meats, smoked foods, cold cuts, or canned foods is believed to contribute to carcinogenesis as they directly affect epithlial turnover and cause metabolism of biliary acids. Dietary fibers have protective effects in that they capture the fats and biliary acids, thereby inhibiting their activity. Tobacco smoking acts both locally and systemically on the colorectal mucosa through the production of carcinogenic agents. Finally, the action of alcohol, in association with nicotine addiction, also increases the risk of developing colorectal tumors. Knowledge of dietary and environmental factors is of paramount importance in implementing preventive strategies for colorectal cancer. |
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Authors:
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Alessandro Cappellani; Antonio Zanghì; Maria Di Vita; Andrea Cavallaro; Gaetano Piccolo; Pierfrancesco Veroux; Emanuele Lo Menzo; Vincenzo Cavallaro; Paolo de Paoli; Massimiliano Veroux; Massimiliano Berretta |
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Publication Detail:
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Type: Journal Article Date: 2013-01-01 |
Journal Detail:
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Title: Frontiers in bioscience : a journal and virtual library Volume: 18 ISSN: 1093-4715 ISO Abbreviation: Front. Biosci. Publication Date: 2013 |
Date Detail:
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Created Date: 2013-01-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9709506 Medline TA: Front Biosci Country: United States |
Other Details:
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Languages: eng Pagination: 190-8 Citation Subset: IM |
Affiliation:
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Department of Surgery, General Surgery and Breast Unit, University of Catania, Azienda Ospedaliero, Universitaria Policlinico, Vittorio Emanuele, via S. Sofia, 78 - 95123 Catania Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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