Document Detail


Stromal cell-immune cell interactions.
MedLine Citation:
PMID:  21073333     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Interaction between different types of hematopoietic cells is essential for proper functioning of the immune system. For instance, the cytokines produced by antigen-presenting dendritic cells will determine the type of T cell response that is induced. However, hematopoietic cells are also strongly influenced by the surrounding nonhematopoietic cells. The cells that form these microenvironments are collectively called stromal cells. Here, we focus on the stromal cells present within secondary lymphoid organs and discuss their importance for various aspects of the immune system.
Authors:
Ramon Roozendaal; Reina E Mebius
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Annual review of immunology     Volume:  29     ISSN:  1545-3278     ISO Abbreviation:  Annu. Rev. Immunol.     Publication Date:  2011  
Date Detail:
Created Date:  2011-03-23     Completed Date:  2011-06-08     Revised Date:  2012-05-01    
Medline Journal Info:
Nlm Unique ID:  8309206     Medline TA:  Annu Rev Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  23-43     Citation Subset:  IM    
Affiliation:
Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands. r.roozendaal@vumc.nl
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MeSH Terms
Descriptor/Qualifier:
Animals
Antigen Presentation
B-Lymphocytes / cytology
Cell Communication
Dendritic Cells / immunology
Humans
Inflammation
Lymphoid Tissue / cytology*,  immunology*
Stromal Cells / cytology*,  immunology*
T-Lymphocytes / cytology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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