Document Detail

Stroke in pregnancy associated with syphilis.
MedLine Citation:
PMID:  18588615     Owner:  NLM     Status:  MEDLINE    
The Incidence of Syphilis has increased in developed countries over recent years. This potentially could lead to a rise in the number of cases presenting in obstetrics and a resurgence of congenital syphilis. Syphilis is a treatable condition, screening in pregnancy is both cost effective and cost beneficial. We describe a rare presentation of syphilis in a young woman in early pregnancy. The patient presented with a stroke, at which time her partner was diagnosed with early latent syphilis. Her findings were thought to be consistent with meningovascular syphilis and treatment lead to resolution of her symptoms. Antenatal screening for syphilis is offered to all women in the UK. Changing migration patterns and high-risk behavior however, may cause cases to go undetected. Vigilant screening for syphilis is needed in pregnancy as prompt diagnosis and management will aim to cure the mother whilst preventing the adverse effects associated with congenital syphilis.
Julie Bowring; Mrinalini Mahto; Debashis Mandal; Philip N Baker
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  34     ISSN:  1341-8076     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-30     Completed Date:  2008-09-04     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  405-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, West Middlesex University Hospital, Twickenham Road, Isleworth, Middlesex, UK.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Aspirin / therapeutic use
Gestational Age
Magnetic Resonance Imaging
Penicillin G / therapeutic use
Penicillin G Procaine / therapeutic use
Pregnancy Complications, Cardiovascular / diagnosis*
Pregnancy Complications, Infectious / diagnosis*
Probenecid / therapeutic use
Stroke / complications*,  diagnosis
Syphilis / complications*,  diagnosis,  drug therapy
Reg. No./Substance:
0/Anti-Bacterial Agents; 50-78-2/Aspirin; 57-66-9/Probenecid; 61-33-6/Penicillin G; 6130-64-9/Penicillin G Procaine

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