Document Detail

Stroke after varicose vein foam injection sclerotherapy.
MedLine Citation:
PMID:  16414404     Owner:  NLM     Status:  MEDLINE    
This report describes an ischemic stroke after foam injection sclerotherapy of varicose veins in a patient with a patent foramen ovale. Foam injection sclerotherapy has created resurgence in the minimally invasive treatment of varicose veins. The United States Food and Drug Administration halted a clinical phase 2 trial of a commercial preparation of polidocanol microfoam in 2003 because of concerns relating to possible gas embolism. These trials were recommenced in July 2005. Neurologic complications such as transient visual disturbances and transient confusional states have previously been reported. This case, with its strong circumstantial evidence, illustrates the previously unconfirmed potential for embolic complications using this technique.
Martin V Forlee; Maria Grouden; Dermot J Moore; Gregor Shanik
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  43     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-17     Completed Date:  2006-02-22     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  162-4     Citation Subset:  IM    
Department of Vascular and Endovascular Surgery, St James Hospital, Dublin, Ireland.
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MeSH Terms
Middle Aged
Polyethylene Glycols / adverse effects*
Sclerosing Solutions / adverse effects*
Sclerotherapy / adverse effects*
Stroke / etiology*
Varicose Veins / therapy*
Reg. No./Substance:
0/Polyethylene Glycols; 0/Sclerosing Solutions; 9002-92-0/polidocanol
Comment In:
J Vasc Surg. 2006 Jul;44(1):225; author reply 225-6   [PMID:  16828455 ]
J Vasc Surg. 2006 Jul;44(1):224-5; author reply 225-6   [PMID:  16828453 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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