Document Detail

Stroke Risk in Poliomyelitis Survivors: A Nationwide Population-based Study.
MedLine Citation:
PMID:  22771481     Owner:  NLM     Status:  Publisher    
OBJECTIVES: To assess the prevalence and risk of stroke among adults with polio and the controls. DESIGN: A prospective, probability-sampling, 6-year population-based cohort study. SETTING: A National Health Insurance Research Database consisting of 316,355 randomly selected enrollees. The database is related to a national health insurance program with more than 22 million participants. PARTICIPANTS: After excluding patients under 40 years of age, a total of 212 polio patients (mean age±SD, 54.0±10.2 years; 57.1% male) were identified from the database from January 1, 2003 to December 31, 2008. For each polio patient, two age- and gender-matched patients were recruited as controls. Control patients did not have any neuromuscular diseases commonly found in childhood. The frequencies of patients with potential risk factors for stroke were assessed. INTERVENTION: None. MAIN OUTCOME MEASURES: The prevalence and the adjusted odds ratio of ischemic stroke among polio patients and the controls were estimated. RESULTS: Polio patients had a higher prevalence of stroke (10.8% vs. 2.4%,p <0.001) than the controls did. Those polio patients with hypertension had much higher prevalence of stroke of 23.0%. The risk of stroke was higher for polio patients compared to the controls, yielding an adjusted odds ratio (95% confidence interval) of 4.17 (1.84-9.45,p < 0.001). Polio was a significant risk factor for stroke independent from hypertension, diabetes mellitus, hyperlipidemia, and cardiac diseases. CONCLUSIONS: Adults with polio had high prevalence of ischemic stroke. Polio was an additional risk factor for stroke. Polio patients with hypertension might potentiate the risk of stroke. Developing a health promotion program, suitable for polio patients, to increase their participation in activities and exercises may be essential, especially for polio patients with hypertension.
Chien-Hua Wu Phd; Tsan-Hon Liou; Hung-Hsin Chen Pt; Tien-Yu Sun; Kai-Hui Chen; Kwang-Hwa Chang
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-4
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  -     ISSN:  1532-821X     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 the American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Department of Applied Mathematics, Chung-Yuan Christian University, Chung-Li, Taiwan.
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