Document Detail

Striatal dopamine after cortical injury: a reexamination.
MedLine Citation:
PMID:  3582563     Owner:  NLM     Status:  MEDLINE    
We reevaluated the effects of unilateral sensorimotor cortex ablation on dopamine and dihydroxyphenylacetic acid concentration in the left and right neostriatum. We found no evidence for an asymmetry of either dopamine or dihydroxyphenylacetic acid in control or sham-operated animals and cortical ablation had no effect on dopamine or dihydroxyphenylacetic acid concentrations. These results suggest that the influence of sensorimotor cortex lesions on extrapyramidal function does not involve changes in striatal dopamine concentrations or turnover.
J P Veinot; M R Peterson; H A Robertson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experimental neurology     Volume:  97     ISSN:  0014-4886     ISO Abbreviation:  Exp. Neurol.     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-07-17     Completed Date:  1987-07-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370712     Medline TA:  Exp Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  207-11     Citation Subset:  IM    
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MeSH Terms
3,4-Dihydroxyphenylacetic Acid / metabolism
Cerebral Cortex / physiology*
Corpus Striatum / metabolism*
Dopamine / metabolism*
Rats, Inbred Strains
Reg. No./Substance:
102-32-9/3,4-Dihydroxyphenylacetic Acid

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