| Stressful life events and daily stressors affect awakening cortisol level in midlife mothers of individuals with autism spectrum disorders. | |
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MedLine Citation:
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PMID: 22640177 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The current study examines the awakening cortisol level in midlife mothers (M = 51.4 years old, SD = 8.4) of individuals (M = 22.1 years old, SD = 7.1) with autism spectrum disorders (ASD) under stressful conditions that are not specific to their son or daughter's ASD symptoms. METHODS: In addition to completing a set of questionnaires and in-home interviews, 82 mothers from the Adolescents and Adults with Autism Study (AAA) participated in a Daily Diary Study. RESULTS: Findings from the multilevel models indicated that mothers who previously were exposed to no negative life events in the previous period had an increased awakening cortisol level on days following a greater number and more severe stressors, a normative stress response. In contrast, we observed a flatter cortisol level of daily stressors in mothers who experienced a greater number of negative life events in the previous period. CONCLUSION: These findings highlight the sustained toll that global and everyday stressors have on awakening cortisol level of midlife and aging mothers of individuals with ASD. |
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Authors:
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Jen D Wong; Marsha M Seltzer; Jan S Greenberg; Jinkuk Hong; David M Almeida; Christopher L Coe |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2012-05-29 |
Journal Detail:
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Title: Aging & mental health Volume: 16 ISSN: 1364-6915 ISO Abbreviation: Aging Ment Health Publication Date: 2012 |
Date Detail:
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Created Date: 2012-10-10 Completed Date: 2013-01-28 Revised Date: 2013-04-16 |
Medline Journal Info:
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Nlm Unique ID: 9705773 Medline TA: Aging Ment Health Country: England |
Other Details:
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Languages: eng Pagination: 939-49 Citation Subset: IM |
Affiliation:
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Waisman Center, University of Wisconsin-Madison, Madison, WI, USA. jwong@waisman.wisc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Activities of Daily Living
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psychology Adolescent Adult Aging / physiology, psychology Autistic Disorder / diagnosis, psychology* Child Female Humans Hydrocortisone / metabolism* Life Change Events* Male Mother-Child Relations Mothers / psychology*, statistics & numerical data Questionnaires Saliva / metabolism* Severity of Illness Index Socioeconomic Factors Stress, Psychological / epidemiology*, metabolism Wakefulness |
| Grant Support | |
ID/Acronym/Agency:
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P30 HD03352/HD/NICHD NIH HHS; R01 AG008768/AG/NIA NIH HHS; R01AG08768/AG/NIA NIH HHS; T32 HD007489/HD/NICHD NIH HHS; T32 HD07489/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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