Document Detail


Stressful life events and daily stressors affect awakening cortisol level in midlife mothers of individuals with autism spectrum disorders.
MedLine Citation:
PMID:  22640177     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The current study examines the awakening cortisol level in midlife mothers (M = 51.4 years old, SD = 8.4) of individuals (M = 22.1 years old, SD = 7.1) with autism spectrum disorders (ASD) under stressful conditions that are not specific to their son or daughter's ASD symptoms.
METHODS: In addition to completing a set of questionnaires and in-home interviews, 82 mothers from the Adolescents and Adults with Autism Study (AAA) participated in a Daily Diary Study.
RESULTS: Findings from the multilevel models indicated that mothers who previously were exposed to no negative life events in the previous period had an increased awakening cortisol level on days following a greater number and more severe stressors, a normative stress response. In contrast, we observed a flatter cortisol level of daily stressors in mothers who experienced a greater number of negative life events in the previous period.
CONCLUSION: These findings highlight the sustained toll that global and everyday stressors have on awakening cortisol level of midlife and aging mothers of individuals with ASD.
Authors:
Jen D Wong; Marsha M Seltzer; Jan S Greenberg; Jinkuk Hong; David M Almeida; Christopher L Coe
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-05-29
Journal Detail:
Title:  Aging & mental health     Volume:  16     ISSN:  1364-6915     ISO Abbreviation:  Aging Ment Health     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-10     Completed Date:  2013-01-28     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  9705773     Medline TA:  Aging Ment Health     Country:  England    
Other Details:
Languages:  eng     Pagination:  939-49     Citation Subset:  IM    
Affiliation:
Waisman Center, University of Wisconsin-Madison, Madison, WI, USA. jwong@waisman.wisc.edu
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MeSH Terms
Descriptor/Qualifier:
Activities of Daily Living / psychology
Adolescent
Adult
Aging / physiology,  psychology
Autistic Disorder / diagnosis,  psychology*
Child
Female
Humans
Hydrocortisone / metabolism*
Life Change Events*
Male
Mother-Child Relations
Mothers / psychology*,  statistics & numerical data
Questionnaires
Saliva / metabolism*
Severity of Illness Index
Socioeconomic Factors
Stress, Psychological / epidemiology*,  metabolism
Wakefulness
Grant Support
ID/Acronym/Agency:
P30 HD003352/HD/NICHD NIH HHS; P30 HD03352/HD/NICHD NIH HHS; R01 AG008768/AG/NIA NIH HHS; R01AG08768/AG/NIA NIH HHS; R24 HD041025/HD/NICHD NIH HHS; T32 HD007489/HD/NICHD NIH HHS; T32 HD07489/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
50-23-7/Hydrocortisone
Comments/Corrections

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