Document Detail

Stress responses of rats with septal lesions.
MedLine Citation:
PMID:  538058     Owner:  NLM     Status:  MEDLINE    
Rats which had received septal lesions or underwent control surgery were exposed to stress in four experiments. We examined plasma corticosterone (Experiment 1), gastric ulceration (Experiment 2), motor activity (Experiment 3) and whole brain norepinephrine (Experiment 4) following 3 hours of prone-restraint-stress conditions at 21 degrees C or 5 degrees C. Rats with special lesions had higher steroids, less severe ulceration, greater motor activity and higher brain norepinephrine than controls following stress. Changes in hyperemotionality and differences in coping strategies are discussed.
J Brick; R G Burright; P J Donovick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pharmacology, biochemistry, and behavior     Volume:  11     ISSN:  0091-3057     ISO Abbreviation:  Pharmacol. Biochem. Behav.     Publication Date:  1979 Dec 
Date Detail:
Created Date:  1980-05-30     Completed Date:  1980-05-30     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0367050     Medline TA:  Pharmacol Biochem Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  695-700     Citation Subset:  IM    
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MeSH Terms
Brain / anatomy & histology,  metabolism,  physiology*
Corticosterone / metabolism
Motor Activity / physiology
Norepinephrine / metabolism
Restraint, Physical
Stomach Ulcer / chemically induced
Stress, Physiological / metabolism,  physiopathology*
Reg. No./Substance:
50-22-6/Corticosterone; 51-41-2/Norepinephrine

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