Document Detail

Stress and oesophageal motility in normal subjects and patients with irritable bowel syndrome.
MedLine Citation:
PMID:  2599439     Owner:  NLM     Status:  MEDLINE    
Patterns of oesophageal motility were recorded in 17 healthy volunteers and 12 patients with the irritable bowel syndrome. Recordings were taken at rest and under stress by hyperventilation, a dichotic hearing challenge and a cold pressor test. In healthy volunteers the dichotic hearing challenge was associated with a significant increase in the mean amplitude of oesophageal peristalsis from 69.9 mmHg to 82.4 mmHg (p less than 0.01) and in the percentage of simultaneous waves from 9.7% to 24.5% (p less than 0.01). The cold pressor test increased the peristaltic amplitude from 69.9 mmHg to 87.1 mmHg (p less than 0.001) and the percentage of simultaneous waves from 9.7% to 34.4% (p less than 0.01). Both manoeuvres were associated with increases in pulse and blood pressure. In patients with irritable bowel syndrome, the resting mean oesophageal peristaltic amplitude was higher than that seen in normal volunteers (95.9 mmHg v 69.9 mmHg p less than 0.05). Changes in oesophageal motility during stress were similar in these patients to those seen in normal subjects although the changes were not significant. This study refutes the hypothesis that symptoms of irritable bowel syndrome and their association with stress are attributable to increased sensitivity of oesophageal motility to disruption by stressful stimuli.
R C Ayres; D A Robertson; K Naylor; C L Smith
Related Documents :
14712899 - Guillain-barré syndrome associated with acute neurobrucellosis.
21623979 - Primary sjögren syndrome in a 2-year-old patient: role of the dentist in diagnosis and ...
14687449 - Utilization patterns and net direct medical cost to medicaid of irritable bowel syndrome.
8001479 - Posterior interosseous syndrome in acute guillain-barré syndrome.
14425069 - The significance of irritability, behaviouristic avoidance and allied phenomena in mala...
14504329 - Csf hypocretin levels in guillain-barré syndrome and other inflammatory neuropathies.
23913389 - Short communication mutations in nphs2 (podocin) in mexican children with nephrotic syn...
17114909 - Oxidative stress in the metabolic syndrome.
8155019 - Carpal tunnel syndrome and hand-arm vibration syndrome. a diagnostic enigma.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gut     Volume:  30     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-02-02     Completed Date:  1990-02-02     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1540-3     Citation Subset:  AIM; IM    
Department of Medicine 2, Southampton General Hospital, Hampshire.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Colonic Diseases, Functional / complications,  physiopathology*
Esophageal Motility Disorders / etiology
Esophagus / physiopathology*
Middle Aged
Reference Values
Stress, Physiological / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Physical characteristics of indigestible solids affect emptying from the fasting human stomach.
Next Document:  Effect of sucralfate on gastric mucosal blood flow in rats.