| Stress echocardiography for selecting potential responders to cardiac resynchronisation therapy. | |
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MedLine Citation:
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PMID: 20610460 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the current ESC/ACC/AHA guidelines, the selection of patients for cardiac resynchronisation therapy (CRT) is based upon the QRS duration, which reflects interventricular dyssynchrony. However, about 30% of patients do not respond to CRT. It has previously been demonstrated that the presence of left ventricular mechanical dyssynchrony is predictive of response to CRT after implantation. Most criteria assessing such dyssynchrony were derived from data obtained with resting Doppler echocardiography. The recently published PROSPECT (Predictors of Response to CRT) trial failed to identify echocardiographic measures of dyssynchrony that could routinely be recommended for patient selection before CRT implantation. Therefore, solutions may come from other echocardiographic modalities, such as dobutamine stress echocardiography and exercise echocardiography. The purpose of this review is to evaluate the usefulness of stress echocardiography to predict response to CRT. This review will show how exercise-induced changes in dyssynchrony and severity of mitral regurgitation and the role of preserved contractile reserve may help to better identify potential responders. |
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Authors:
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Marie Moonen; Kim O'Connor; Julien Magne; Patrizio Lancellotti; Luc A Pierard |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Heart (British Cardiac Society) Volume: 96 ISSN: 1468-201X ISO Abbreviation: Heart Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-08-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9602087 Medline TA: Heart Country: England |
Other Details:
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Languages: eng Pagination: 1142-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, University Hospital Sart Tilman, Liège, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Pacing, Artificial* Echocardiography, Stress / methods Heart Failure / complications, physiopathology, therapy*, ultrasonography* Humans Patient Selection Ventricular Dysfunction, Left / etiology, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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