Document Detail


Stress and allergic diseases.
MedLine Citation:
PMID:  21094923     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Allergy describes a constellation of clinical diseases that affect up to 30% of the world's population. It is characterized by production of allergen-specific IgE, which binds to mast cells and initiates a cascade of molecular and cellular events that affect the respiratory tract (rhinitis and asthma), skin (dermatitis, urticaria), and multiple systems (anaphylaxis) in response to a variety of allergens including pollens, mold spores, animal danders, insect stings, foods, and drugs. The underlying pathophysiology involves immunoregulatory dysfunctions similar to those noted in highly stressed populations. The relationships in terms of potential for intervention are discussed.
Authors:
Ninabahen D Dave; Lianbin Xiang; Kristina E Rehm; Gailen D Marshall
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Immunology and allergy clinics of North America     Volume:  31     ISSN:  1557-8607     ISO Abbreviation:  Immunol Allergy Clin North Am     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2010-11-24     Completed Date:  2011-05-24     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  8805635     Medline TA:  Immunol Allergy Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  55-68     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Laboratory of Behavioral Immunology Research, Division of Clinical Immunology and Allergy, Department of Medicine, The University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505, USA. ndave@umc.edu
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MeSH Terms
Descriptor/Qualifier:
Asthma / immunology,  psychology
Disease Management
Humans
Hypersensitivity, Immediate / immunology,  psychology*
Immunoglobulin E / immunology
Immunomodulation
Inflammation / immunology,  psychology*
Stress, Psychological / immunology*
Grant Support
ID/Acronym/Agency:
1 CPI MP061018-02/MP/OMH OASH HHS; 1 R21 HL96086-01/HL/NHLBI NIH HHS; 5 R21 AT002938-02/AT/NCCAM NIH HHS; R01 HL061018-02/HL/NHLBI NIH HHS; R21 AT002938-01A1S1/AT/NCCAM NIH HHS; R21 AT002938-02/AT/NCCAM NIH HHS; R21 HL096086-01A1/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
37341-29-0/Immunoglobulin E
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