Document Detail


Stress ulcer prophylaxis: reducing non-indicated prescribing after hospital discharge.
MedLine Citation:
PMID:  20841521     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Gastric acid suppressant medications used as stress ulcer prophylaxis (SUP) in the intensive care unit (ICU) are often prescribed inappropriately after discharge. We present tools to reduce the use and cost of non-indicated SUP.
OBJECTIVE: To reduce the non-indicated use of SUP after hospital discharge originally started in the ICU, using an education intervention and pharmacist-led medication reconciliation on patient care rounds and at hospital discharge.
METHODS: In a retrospective medical record review using a historic control, 356 consecutively admitted patients to the medical/surgical ICU at the University of Wisconsin Hospital were assessed for the appropriate use of SUP at admission to the ICU, at transfer to a general care unit, and at hospital discharge. The education intervention involved teaching both the medical and pharmacist staff about indications for SUP using a memorandum and a pocket guide. Pharmacists also conducted medication reconciliation during daily patient care rounds and at discharge to justify medication use. The outcome of this study is the percentage of patients prescribed non-indicated gastric acid suppressants at hospital discharge. This outcome is compared to a previous study conducted at our hospital.
RESULTS: Of 356 eligible patients, 308 (86.5%) received SUP while in the ICU. Thirty-nine (11%) were given continuing SUP after discharge from the hospital, of which 31 (8.7%) had no clear indication. This was a 64.3% reduction from the 24.4% found in the prior study (p < 0.0001).
CONCLUSIONS: Educational materials that guide prescribing, pharmacist interaction on patient care rounds, and pharmacist-conducted medication reconciliation significantly reduced the prescribing of non-indicated gastric acid suppressant medications after hospital discharge.
Authors:
Jacob B Hatch; Lucas Schulz; Jeffrey T Fish
Publication Detail:
Type:  Journal Article     Date:  2010-09-14
Journal Detail:
Title:  The Annals of pharmacotherapy     Volume:  44     ISSN:  1542-6270     ISO Abbreviation:  Ann Pharmacother     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-23     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203131     Medline TA:  Ann Pharmacother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1565-71     Citation Subset:  IM    
Affiliation:
Department of Pharmacy Services, University of Wisconsin Hospital and Clinics, Madison, USA. jhatch@uwhealth.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anti-Ulcer Agents / administration & dosage,  economics,  therapeutic use*
Continuity of Patient Care
Drug Utilization
Female
Health Care Costs
Hospitals, University
Humans
Inappropriate Prescribing*
Intensive Care Units
Male
Medication Reconciliation*
Middle Aged
Patient Discharge*
Patient Education as Topic
Peptic Ulcer / economics,  etiology,  prevention & control*
Pharmacists
Pharmacy Service, Hospital
Professional Role
Retrospective Studies
Stress, Psychological / complications,  economics,  prevention & control*
Chemical
Reg. No./Substance:
0/Anti-Ulcer Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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