Document Detail

Streptococcus pneumoniae sepsis in the newborn.
MedLine Citation:
PMID:  21199057     Owner:  NLM     Status:  Publisher    
Background:  Streptococcus pneumoniae (SP) is an uncommon cause of neonatal sepsis. Aims:  To report on the spectrum of morbidity associated with SP infections in the neonatal period. Methods:  A case series of SP infection in the neonatal period was studied. Maternal and neonatal outcomes were noted. Results:  Four cases of neonatal SP infection are reported, one of which was due to a strain with reduced susceptibility to penicillin. All four cases had very early onset of severe clinical disease with bacteremia and pneumonia. In one case a retrospective diagnosis of meningitis was made as well. Maternal illness was a feature in one of these infants. Conclusions:  Although less common now than in the pre-antibiotic era, Streptococcus pneumoniae remains a rare but important cause of neonatal sepsis and can mimic early onset Group B streptococcal sepsis. It is unclear whether current infant or adult pneumococcal immunisation programs might influence its incidence in the neonatal period. The potential for strains with reduced susceptibility to β-lactam antibiotics to cause neonatal infection needs to be considered in relevant settings.
Atul Malhotra; Rod W Hunt; Richard R Doherty
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-29
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  -     ISSN:  1440-1754     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-1-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2010 The Authors. Journal of Paediatrics and Child Health © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
Monash Newborn Department of Paediatric Infectious Diseases Unit, Monash Children's Neonatal Unit, Royal Children's Hospital Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.
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