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Streptococcus pneumoniae sepsis in the newborn.
MedLine Citation:
PMID:  21199057     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background:  Streptococcus pneumoniae (SP) is an uncommon cause of neonatal sepsis. Aims:  To report on the spectrum of morbidity associated with SP infections in the neonatal period. Methods:  A case series of SP infection in the neonatal period was studied. Maternal and neonatal outcomes were noted. Results:  Four cases of neonatal SP infection are reported, one of which was due to a strain with reduced susceptibility to penicillin. All four cases had very early onset of severe clinical disease with bacteremia and pneumonia. In one case a retrospective diagnosis of meningitis was made as well. Maternal illness was a feature in one of these infants. Conclusions:  Although less common now than in the pre-antibiotic era, Streptococcus pneumoniae remains a rare but important cause of neonatal sepsis and can mimic early onset Group B streptococcal sepsis. It is unclear whether current infant or adult pneumococcal immunisation programs might influence its incidence in the neonatal period. The potential for strains with reduced susceptibility to β-lactam antibiotics to cause neonatal infection needs to be considered in relevant settings.
Authors:
Atul Malhotra; Rod W Hunt; Richard R Doherty
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-29
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  -     ISSN:  1440-1754     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-1-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2010 The Authors. Journal of Paediatrics and Child Health © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
Affiliation:
Monash Newborn Department of Paediatric Infectious Diseases Unit, Monash Children's Neonatal Unit, Royal Children's Hospital Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.
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