| Streptococcus pneumoniae sepsis in the newborn. | |
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MedLine Citation:
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PMID: 21199057 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Streptococcus pneumoniae (SP) is an uncommon cause of neonatal sepsis. Aims: To report on the spectrum of morbidity associated with SP infections in the neonatal period. Methods: A case series of SP infection in the neonatal period was studied. Maternal and neonatal outcomes were noted. Results: Four cases of neonatal SP infection are reported, one of which was due to a strain with reduced susceptibility to penicillin. All four cases had very early onset of severe clinical disease with bacteremia and pneumonia. In one case a retrospective diagnosis of meningitis was made as well. Maternal illness was a feature in one of these infants. Conclusions: Although less common now than in the pre-antibiotic era, Streptococcus pneumoniae remains a rare but important cause of neonatal sepsis and can mimic early onset Group B streptococcal sepsis. It is unclear whether current infant or adult pneumococcal immunisation programs might influence its incidence in the neonatal period. The potential for strains with reduced susceptibility to β-lactam antibiotics to cause neonatal infection needs to be considered in relevant settings. |
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Authors:
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Atul Malhotra; Rod W Hunt; Richard R Doherty |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-12-29 |
Journal Detail:
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Title: Journal of paediatrics and child health Volume: - ISSN: 1440-1754 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2011-1-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9005421 Medline TA: J Paediatr Child Health Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2010 The Authors. Journal of Paediatrics and Child Health © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians). |
Affiliation:
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Monash Newborn Department of Paediatric Infectious Diseases Unit, Monash Children's Neonatal Unit, Royal Children's Hospital Department of Paediatrics, Monash University, Melbourne, Victoria, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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