| Strength training following hematopoietic stem cell transplantation. | |
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MedLine Citation:
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PMID: 21116175 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Patients receiving high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT) experience considerable reductions in physical activity and deterioration of their health status. OBJECTIVE: The purpose of this pilot study was to test the effects of strength training compared with usual activity on physical activity, muscle strength, fatigue, health status perceptions, and quality of life following HSCT. METHODS: Nineteen subjects were randomized to the exercise or control group. Moderate-intensity strength training began following discharge from the hospital. Dependent variables included physical activity, muscle strength, fatigue, health status perceptions, and quality of life. Variables were measured prior to admission to the hospital for HSCT, day 8 following HSCT, and 6 weeks following discharge from the hospital. RESULTS: Significant time effects were noted for many variables with anticipated declines in physical activity, muscle strength, fatigue, and health status perceptions immediately after HSCT with subsequent improvements 6 weeks following hospital discharge. One group effect was noted with subjects in the exercise group reporting less fatigue than subjects in the control group. Although no significant interactions were detected, the trends suggest that the exercise group may be more physically active following the intervention compared with the usual-activity group. CONCLUSIONS: This study demonstrates the potential positive effects of strength training on physical activity, fatigue, and quality of life in people receiving high-dose chemotherapy and HSCT. IMPLICATIONS FOR PRACTICE: Preliminary evidence is provided for using strength training to enhance early recovery following HSCT. Elastic resistance bands are easy to use and relatively inexpensive. |
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Authors:
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Eileen Danaher Hacker; Janet Larson; Amber Kujath; David Peace; Damiano Rondelli; Lisa Gaston |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Cancer nursing Volume: 34 ISSN: 1538-9804 ISO Abbreviation: Cancer Nurs Publication Date: 2011 May-Jun |
Date Detail:
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Created Date: 2011-04-22 Completed Date: 2011-08-29 Revised Date: 2012-05-02 |
Medline Journal Info:
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Nlm Unique ID: 7805358 Medline TA: Cancer Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 238-49 Citation Subset: IM; N |
Copyright Information:
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© 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins |
Affiliation:
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University of Illinois at Chicago, College of Nursing, Department of Biobehavioral Health Science (M/C 802), 845 S Damen Ave, Room 718 NURS, Chicago, IL 60612, USA. ehacker@uic.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Actigraphy
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instrumentation Adult Aged Analysis of Variance Exercise Test Exercise Therapy* Fatigue / etiology, nursing, psychology, therapy* Female Health Status Indicators Hematopoietic Stem Cell Transplantation / adverse effects* Humans Isometric Contraction / physiology* Male Middle Aged Motor Activity Muscle Strength / physiology* Muscle, Skeletal / physiology* Pilot Projects Quality of Life / psychology Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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K01 NR009375/NR/NINR NIH HHS; K01 NR009375-01/NR/NINR NIH HHS; K01 NR009375-02/NR/NINR NIH HHS; K01 NR009375-03/NR/NINR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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