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Strawberries on the brain. Intracranial capillary hemangioma: Two case reports and systematic literature review in children and adults.
MedLine Citation:
PMID:  23247022     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Capillary hemangioma in the cranial cavity is rare. This report presents two additional cases with onset of symptoms in relation to pregnancy and provide a systematic review summarizing clinical experience to date. METHODS: Case reports were compiled retrospectively. Patient 1: A 28 year old woman presented with a simple partial seizure associated with left-sided visual distortions which progressed to a secondary generalised tonic clonic seizure. Imaging revealed a contrast-enhancing lesion in the right temporal region adjacent to the transverse sinus, with vasogenic edema and scalloping of the inner table. Angiographic appearance suggested the correct diagnosis. Patient 2: A 41 year-old woman presented with progressive visual disturbance 6 months after giving birth to her second child. Subtle symptoms of headache and visual disturbance had commenced during pregnancy. Non-contrasted imaging displayed a homogenous tumor with surrounding vasogenic edema in the occipital region. The publications on PubMed and Science Citation Index were reviewed systematically. RESULTS: Complete surgical excision was performed in both patients. Neuropathological examination confirmed benign capillary hemangioma consisting of a mesh-work of capillary sized and larger feeder vessels in both instances. The systematic review was based on 20 publications and clinical, radiological and surgical features together with the management were summarized. CONCLUSION: At follow-up, symptoms had disappeared and MRI confirmed complete removal in both patients. Intracranial capillary hemangioma is rare and treatment is empirical. Review of limited published reports suggested that surgery is the most commonly used treatment and that complete excision appears most likely to prevent further recurrence.
Bilal Mirza; William Y Shi; Rahul Phadke; Janice L Holton; Chris Turner; Gordon T Plant; Stefan Brew; Neil Kitchen; Ludvic Zrinzo
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-13
Journal Detail:
Title:  World neurosurgery     Volume:  -     ISSN:  1878-8750     ISO Abbreviation:  World Neurosurg     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101528275     Medline TA:  World Neurosurg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Victor Horsley Department of Neurosurgery, The National Hospital for Neurology & Neurosurgery, Queen Square, London, WC1N 3BG, UK. Electronic address:
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