Document Detail

Strategy of insulin intensification after Basal failure for type 2 diabetes in the outpatient setting.
MedLine Citation:
PMID:  21785179     Owner:  NLM     Status:  In-Data-Review    
Type 2 diabetes has become a worldwide pandemic and the problem continues to grow. As the disease progresses, the majority of patients will require insulin therapy within 6 years of diagnosis. During the therapy, evaluation and intensification of the current treatment is required in order to achieve the good glycaemic state. In patients who are taking basal insulin or premix OD but failing to achieve the recommended glycaemic targets of HbA1c <6.5%-7%, one option is to intensify to a modern premixed insulin BID or TID. Its formulations have both basal and short or rapid-acting insulin capabilities, enabling them to cover both fasting and postprandial blood glucose levels. Other strategy is known as basal-plus method, basal plus 1 and then basal plus 2. This strategy is used by adding OD short-acting or rapid-acting insulin (analog) before having largest portion meal or before meal when blood glucose before the next meal is high. It is very important for clinicians to have the capability of choosing the right regimen based on individual's need and applying the right strategy to intensify the insulin therapy for their patients.
Tri Juli E Tarigan; Yaldiera Utami
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Indonesiana     Volume:  43     ISSN:  0125-9326     ISO Abbreviation:  Acta Med Indones     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-07-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7901042     Medline TA:  Acta Med Indones     Country:  Indonesia    
Other Details:
Languages:  eng     Pagination:  144-7     Citation Subset:  IM    
Department of Internal Medicine, Faculty of Medicine, University Indonesia-dr. Cipto Mangunkusumo Hospital. Jl. Diponegoro no. 71, Jakarta 10430, Indonesia.
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