Document Detail


Strategy of goitre and cretinism control in Central Africa.
MedLine Citation:
PMID:  197032     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Goitre prevalence in Ubangi Mongala (north-western Zaïre) ranges from 27 to 60 per cent in the male population and from 48 to 78 per cent in the female population; the prevalence of cretinism ranges between 0.7 and 7.6 per cent. This severe endemia affects 1.5 million inhabitants and constitutes a major public health problem. If administered to an entire population, single injections of slowly resorbable iodized oil can reduce goitre prevalence substantially, correct the iodine deficiency and restore normal thyroid function for a period of 3 to 7 years, depending on the parameter considered. The cost of programme of endemic goitre prevention based on this method can be estimated at 0.07 US dollars per person and per year of protection. A strategy of goitre and cretinism control in Central Africa, using iodized oil in an attack phase and iodized salt in a follow-up phase, is proposed. The organization of this programme will be dovetailed into other public health activities and will strengthen the basic health service framework.
Goiter prevalence in Ubangi Mongala (northwest Zaire) ranges from 27-60% in the male population and from 48-78% in the female population; the prevalence of cretinism ranges from 0.7-7.6%. The severe endemia affects 1.5 million inhabitants and constitutes a major public health problem. If administered to an entire population, single injections of slowly resorbable iodized oil can reduce goiter prevalence substantially, correct the iodine deficiency, and restore normal thyroid function for a period of 3-7 years, depending on the parameter considered. The cost of such a program of endemic goiter prevention based on this method can be estimated at 0.07 US dollars/person/year of protection. A strategy of goiter and cretinism control in Central Africa, using iodized oil in an attack phase and iodized salt in a follow-up phase is proposed. The organization of this program will be dovetailed into other public health activities and will strengthen the basic health service framework.
Authors:
C H Thilly; F Delange; L Ramioul; R Lagasse; K Luvivila; A M Ermans
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of epidemiology     Volume:  6     ISSN:  0300-5771     ISO Abbreviation:  Int J Epidemiol     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-10-20     Completed Date:  1977-10-20     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7802871     Medline TA:  Int J Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  43-54     Citation Subset:  IM; J    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Congenital Hypothyroidism / drug therapy,  epidemiology,  prevention & control*
Democratic Republic of the Congo
Drug Administration Schedule
Female
Follow-Up Studies
Goiter, Endemic / drug therapy,  epidemiology,  prevention & control*
Humans
Injections, Intramuscular
Iodized Oil / administration & dosage,  therapeutic use
Male
Rural Population
Socioeconomic Factors
Chemical
Reg. No./Substance:
8001-40-9/Iodized Oil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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