Document Detail

Strategies to optimize alveolar recruitment.
MedLine Citation:
PMID:  11373506     Owner:  NLM     Status:  MEDLINE    
Low tidal volume (4-8 mL/kg) during mechanical ventilation in adult respiratory distress syndrome is the standard of care. However, there are questions regarding the approach to setting positive end-expiratory pressure and the use of recruitment maneuvers in patients with adult respiratory distress syndrome. Animal data and preliminary patient data suggest that lung recruitment maneuvers can markedly improve arterial oxygen tension (PaO2). Prone positioning has also become established a method of recruiting lung and improving PaO2 in those with adult respiratory distress syndrome. The data suggest that recruitment maneuvers in the prone position are most effective in improving PaO2 and that the positive end-expiratory pressure level required to sustain the improved PaO2 is less in the prone position than in the supine position.
R M Kacmarek
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Current opinion in critical care     Volume:  7     ISSN:  1070-5295     ISO Abbreviation:  Curr Opin Crit Care     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-06-20     Completed Date:  2001-10-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9504454     Medline TA:  Curr Opin Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  15-20     Citation Subset:  IM    
Department of Anesthesia, Harvard Medical School, Respiratory Care, Massachusetts General Hospital, Boston, Massachusetts, USA.
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MeSH Terms
Disease Models, Animal
Oxygen / blood
Positive-Pressure Respiration / methods*
Prone Position
Pulmonary Alveoli / physiopathology*
Respiration, Artificial / methods*
Respiratory Distress Syndrome, Adult / physiopathology,  therapy*
Tidal Volume
Reg. No./Substance:

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