Document Detail

Strategies to minimize bleeding complications of percutaneous coronary intervention.
MedLine Citation:
PMID:  19474710     Owner:  NLM     Status:  In-Process    
PURPOSE OF REVIEW: Bleeding has recently been identified as a major adverse outcome in patients with acute coronary syndromes. In this review, the importance of the association of bleeding with mortality and strategies to reduce bleeding with percutaneous coronary intervention are discussed. RECENT FINDINGS: Nine trials have shown an association of bleeding with mortality. The influence of major bleeding is at least equivalent to the effect of a myocardial infarction. In order to reduce bleeding, individualized risk assessment should be performed and attention paid to choice of access, antithrombotic, dose of antithrombotic, avoidance of crossing over from one antithrombotic to another, smaller sheaths and early removal as well as choice of P2Y12 inhibitor. SUMMARY: Individualizing treatment and strategies to reduce both ischemic events and bleeding will improve patient outcomes.
Harvey D White
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in cardiology     Volume:  24     ISSN:  1531-7080     ISO Abbreviation:  Curr. Opin. Cardiol.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8608087     Medline TA:  Curr Opin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  273-8     Citation Subset:  IM    
Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.
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