Document Detail


Strategies for the prevention and treatment of sudden cardiac death.
MedLine Citation:
PMID:  22102788     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Cardiovascular diseases account for 40% of all deaths in the West. Sudden cardiac death (SCD) is a major health problem affecting over 300,000 patients annually in the United States alone. Presence of coronary artery disease (CAD), usually in the setting of diminished left ventricular ejection fraction, is still the single major risk factor for SCD. Additionally, acute myocardial ischemia, structural cardiac defects, anomalous coronary arteries, cardiomyopathies, genetic mutations, and ventricular arrhythmias are all attributed to SCD, demonstrating the perplexity of this condition. With the recent advancements in cardiovascular medicine, the incidence of SCD is expected to increase steeply as the prevalence of CAD and heart failure is uprising in general population. Considering SCD, the major challenge confronting contemporary cardiology, multiple strategies for prevention against SCD have been developed. β-blockers have been shown to reduce the risk of SCD, whereas implantable cardioverter-defibrillator devices are found to be effective at terminating the malignant arrhythmias. In recent years, multiple clinical trials were carried out to identify patients who may benefit from preventive intervention, including medical therapy and automatic cardioverter-defibrillator implantations. This review article provides insight into the advanced strategies for the prevention and treatment of SCD based on the data available in medical literature to date.
Authors:
Emad F Aziz; Fahad Javed; Balaji Pratap; Eyal Herzog
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Open access emergency medicine : OAEM     Volume:  2010     ISSN:  1179-1500     ISO Abbreviation:  Open Access Emerg Med     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-11-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101570796     Medline TA:  Open Access Emerg Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  99-114     Citation Subset:  -    
Affiliation:
The Advanced Cardiac Admission Program, St Luke's-Roosevelt Hospital Center, University Hospital of Columbia University, College of Physicians and Surgeons, New York, NY, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
P30 DK026687-26//NIDDK NIH HHS; P30 DK026687-27//NIDDK NIH HHS; P30 DK026687-28//NIDDK NIH HHS

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