| Strategies for prevention of feed intolerance in preterm neonates: a systematic review. | |
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MedLine Citation:
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PMID: 16105795 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Postnatal growth restriction and failure to thrive have been recently identified as a major issue in preterm, especially extremely-low-birth-weight neonates. An increased length of time to reach full enteral feedings is also significantly associated with a poorer mental outcome in preterm neonates at 24 months corrected age. Optimization of enteral nutrition without increasing the risk of necrotizing enterocolitis (NEC) has thus become a priority in preterm neonates. A range of feeding strategies currently exists for preventing/minimizing feed intolerance in preterm neonates reflecting the dilemma surrounding the definition and significance of signs of feed intolerance due to ileus of prematurity and the fear of NEC. The results of a systematic review of current strategies for preventing/minimizing feed intolerance in preterm neonates are discussed. The need for clinical research in the area of signs of feed intolerance is emphasized to develop a scientific basis to feeding strategies. Only large pragmatic trials based on such strategies will reveal whether the benefits (improved growth and long term neurodevelopmental outcomes) of aggressive enteral nutrition can outweigh the risks of a potentially devastating illness like NEC, and of prolonged parenteral nutrition in preterm neonates. |
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Authors:
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Sanjay Patole |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: 18 ISSN: 1476-7058 ISO Abbreviation: J. Matern. Fetal. Neonatal. Med. Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-08-17 Completed Date: 2006-01-24 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: United States |
Other Details:
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Languages: eng Pagination: 67-76 Citation Subset: IM |
Affiliation:
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Department of Neonatal Paediatrics, King Edward Memorial Hospital for Women and University of Western Australia, Perth, Australia. Sanjay.Patole@health.wa.gov.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Enteral Nutrition
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adverse effects,
methods* Enterocolitis, Necrotizing / prevention & control* Food Hypersensitivity / prevention & control* Humans Infant Formula Infant Nutritional Physiological Phenomena Infant, Low Birth Weight Infant, Newborn Infant, Premature* Parenteral Nutrition, Total / adverse effects, methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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