Document Detail

Strategies for the infertile man.
MedLine Citation:
PMID:  11679904     Owner:  NLM     Status:  MEDLINE    
Male infertility is one of the most common, identifiable causes of human reproductive failure. Although considerable progress has been made toward understanding sperm physiology and the biology of gamete interaction, still more work is needed to achieve objectivity and standardization of some of the andrological diagnostic methods used in the clinical setting. More information is needed to definitively establish which tests are more accurate predictors of sperm performance and how they correlate with pregnancy potential following in vivo and in vitro interventions. Infertile men can be successfully treated with defined urological and medical therapies or with assisted reproductive technologies (ARTs). Among the latter, intracytoplasmic sperm injection (ICSI) has become a validated means to overcome multiple sperm deficiencies. Nevertheless, it is expected that simplified and more cost-efficient therapeutic modalities will be developed as additional basic (cellular-molecular) and clinical knowledge is gained.
S Oehninger
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in reproductive medicine     Volume:  19     ISSN:  1526-8004     ISO Abbreviation:  Semin. Reprod. Med.     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-10-26     Completed Date:  2002-01-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100909394     Medline TA:  Semin Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  231-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, The Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, Virginia 23507-1627, USA.
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MeSH Terms
Chromosome Aberrations
Infertility, Male / diagnosis*,  therapy*
Sperm Injections, Intracytoplasmic
Sperm-Ovum Interactions / physiology*
Spermatozoa / pathology,  physiology*

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