| Strategies for Designing and Validating Immunostimulatory siRNAs. | |
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MedLine Citation:
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PMID: 23027052 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Specific clinical applications of RNA interference (RNAi) can benefit from a concurrent activation of the immune system. This is the case for small interfering RNAs (siRNAs) with antitumor or antiviral activities. This chapter provides a brief overview of the strategies reported to date to design siRNAs with gene silencing and immune activating properties, as well as methods for the validation of immunostimulatory activities. |
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Authors:
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Michael P Gantier |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methods in molecular biology (Clifton, N.J.) Volume: 942 ISSN: 1940-6029 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2013 |
Date Detail:
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Created Date: 2012-10-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: United States |
Other Details:
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Languages: eng Pagination: 179-91 Citation Subset: IM |
Affiliation:
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Monash Institute of Medical Research, Monash University, Clayton, VIC, Australia, michael.gantier@monash.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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