Document Detail


Strategic treatment of anovular dairy cows with GnRH.
MedLine Citation:
PMID:  18926565     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The primary objective was to evaluate fertility of anovular dairy cows given GnRH 4 d after first postpartum timed AI (TAI). Secondary objectives were to determine ovulatory response to treatment, effect of treatment on serum progesterone (P(4)) concentrations, and the proportion with a short luteal phase. Lactating Holstein cows (n=1047) were submitted for first postpartum TAI using a Presynch+Ovsynch protocol. Anovular cows were identified from an initial 1047 lactating Holstein cows using transrectal ultrasonography, based on the absence of a CL at the first GnRH injection of a Presynch+Ovsynch protocol, and anovular cows were randomly assigned to receive either no further treatment (Control, n=85), or 100 microg of GnRH 4 d after TAI (GnRH treated; n=71). For GnRH treated cows, 51% responded by ovulating a follicle in response to GnRH treatment 4 d after TAI; however, pregnancies per AI (P/AI) did not differ between GnRH treated cows that ovulated (36%) compared to GnRH treated cows that did not ovulate (21%). There was a quadratic effect of P(4) at the PGF(2 alpha) injection of Ovsynch on P/AI, and cows with P(4)>or=1 ng/mL at the PGF(2 alpha) injection of Ovsynch had greater P/AI (41%) than cows with P(4)<1 ng/mL (12%); however, no treatment difference was detected. Overall, P/AI did not differ between control (30.1%) and GnRH treated (29.6%) treatments for synchronized cows. Although treatment of anovular cows with GnRH 4 d after TAI failed to improve fertility, variation among cows in serum P(4) at the PGF(2 alpha) injection of Ovsynch dramatically affected fertility of anovular dairy cows.
Authors:
R A Sterry; E Silva; D Kolb; P M Fricke
Related Documents :
19729195 - Dynamics of heat shock protein 70 concentrations in peripheral blood lymphocyte lysates...
9448825 - Comparison of two estrus synchronization programs in a large, confinement-housed dairy ...
15882405 - The effect on pregnancy rate of progesterone administration after manual reduction of t...
22809485 - Neurobehavior in fetal life.
24405265 - Vasoactive intestinal peptide induces an immunosuppressant microenvironment in the mate...
17651545 - Ocular changes during pregnancy.
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2008-10-15
Journal Detail:
Title:  Theriogenology     Volume:  71     ISSN:  0093-691X     ISO Abbreviation:  Theriogenology     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2008-12-30     Completed Date:  2009-03-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421510     Medline TA:  Theriogenology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  534-42     Citation Subset:  IM    
Affiliation:
Department of Dairy Science, University of Wisconsin, Madison, WI 53706, United States.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Anovulation / veterinary*
Cattle*
Estrus Synchronization / drug effects
Female
Fertility
Fertility Agents, Female / administration & dosage*,  pharmacology*
Gonadotropin-Releasing Hormone / administration & dosage*,  pharmacology*
Infertility
Insemination, Artificial / veterinary
Ovulation / drug effects
Pregnancy
Progesterone / blood
Chemical
Reg. No./Substance:
0/Fertility Agents, Female; 33515-09-2/Gonadotropin-Releasing Hormone; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immun...
Next Document:  Bridging the gap between clinical failure and laboratory fracture strength tests using a fractograph...