Document Detail

Strain rate dobutamine echocardiography for prediction of recovery after revascularization in patients with ischemic left ventricular dysfunction.
MedLine Citation:
PMID:  16679259     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The purpose of the present study was to assess the accuracy of quantitative segmental analysis by strain rate imaging (SRI) technique during dobutamine test for detecting myocardial recovery after revascularization in patients with chronic ischemic regional left ventricular (LV) dysfunction and compare results with those of 2-dimensional echocardiography (2D) and tissue Doppler imaging (TDI) as well as rest-4 hours-24 hours redistribution thallium SPECT (Tl SPECT). METHODS AND RESULTS: Forty-one patients with chronic ischemic regional LV dysfunction (EF 29 +/- 8%) underwent dobutamine 2D/TDI/SRI and Tl SPECT before and after myocardial revascularization. The sensitivity, specificity, and accuracy for the recovery of regional LV function were 73%, 81%, and 77% for dobutamine 2D; 77%, 82%, and 80% for dobutamine TDI; 86%, 88%, and 85% for dobutamine SRI; and 94%, 76%, and 84% for Tl tomography. The area under the ROC curve (AUC), which reflects the overall performance for the prediction of recovery, was 0.79 for systolic-SR, 0.81 for Tl SPECT, 0.83 for postsystolic strain, and 0.87 for isovolumic-SR. If both systolic and postsystolic SRI indexes were combined with Tl SPECT, the AUC was improved to 0.94. CONCLUSIONS: Dobutamine SRI is more accurate than TDI in identifying hibernating myocardium. Systo-diastolic values obtained using dobutamine SRI echocardiography and values derived from nuclear perfusion techniques may be complementary in assessing myocardial viability.
Antonio Vitarelli; Teresa Montesano; Carlo Gaudio; Ysabel Conde; Ester Cimino; Ilaria D'angeli; Simona D'orazio; Simona Stellato; Daniela Battaglia; Viviana Padella; Fiorella Caranci; Massimo Ciancamerla; Angelo Domenico Di Nicola; Giuseppe Ronga
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of cardiac failure     Volume:  12     ISSN:  1532-8414     ISO Abbreviation:  J. Card. Fail.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-08     Completed Date:  2006-09-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9442138     Medline TA:  J Card Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  268-75     Citation Subset:  IM    
La Sapienza University, Rome, Italy.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Area Under Curve
Coronary Angiography
Coronary Artery Bypass*
Echocardiography, Stress / methods*
Image Processing, Computer-Assisted
Middle Aged
Myocardial Contraction
Prospective Studies
Recovery of Function
Sensitivity and Specificity
Tomography, Emission-Computed, Single-Photon
Ventricular Dysfunction, Left / physiopathology,  radionuclide imaging,  surgery,  therapy*,  ultrasonography*

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